18:0 PC (DSPC) / 500 MG
Safety Information
Hazard Statements
Precautionary Statements
Pictograms
Properties
| Signal Word | Danger |
| Flash Point (C) | does not flash |
Product Description
1,2-Distearoyl-sn-glycero-3-phosphocholine is a phospholipid molecule composed of a glycerol backbone, two stearoyl fatty acid chains, a phosphate group, and a choline head group. It is a major component of cell membranes, particularly in mammalian cells.
Application:
This compound is widely used in pharmaceutical formulations, particularly in liposomal drug delivery systems and as a stabilizer in protein formulations. It is also utilized in cosmetic formulations and as a research tool in membrane biology studies.
Articles:
- Calcium-mediated binding of DNA to 1,2-distearoyl-sn-glycero-3-phosphocholine-containing mixed lipid monolayers
Publication Date: 07 Jan 2014
Aleksandra P. Dabkowska, David J. Barlow, Luke A. Clifton, Arwel V. Hughes, John R. P. Webster, Rebecca J. Green, Peter J. Quinn and M. Jayne Lawrence
https://doi.org/10.1039/C3SM52747F
- In Vitro Characterization of a Liposomal Formulation of Celecoxib Containing 1,2-Distearoyl-sn-Glycero-3-Phosphocholine, Cholesterol, and Polyethylene Glycol and its Functional Effects Against Colorectal Cancer Cell Lines
Publication Date: Available online 4 January 2016
Asli Erdoğ, Yanuar Dwi Putra Limasale, Dilek Keskin, Ayşen Tezcaner, Sreeparna Banerjee
https://doi.org/10.1002/jps.23674
- Rapid, one-step fabrication and loading of nanoscale 1,2-distearoyl-sn-glycero-3-phosphocholine liposomes in a simple, double flow-focusing microfluidic device
Publication Date: JULY 01 2015
Ryan V. Tien Sing Young; Maryam Tabrizian