Sodium perchlorate hydrate / 500 g

Sodium perchlorate is useful in DNA extraction and purification processes. Specifically, sodium perchlorate plays a crucial role in the purification of human genomic DNA from whole blood samples. Sodium perchlorate hydrate and chloroform have been developed as alternatives in the method, mentioned above, offering significant time savings and reducing hazards and leading to a more efficient and safer extraction process in comparison with phenol. The DNA extracted using sodium perchlorate is an excellent substrate for restriction endonuclease digestion and Southern hybridization analysis, demonstrating its effectiveness in DNA manipulation and analysis.
Furthermore, sodium perchlorate is used in standard DNA extraction and hybridization reactions in molecular biology. It is particularly effective in isolating nucleic acids from complex starting materials such as blood or tissues, which traditionally require multiple steps involving detergents, enzymes, and organic solvents. Sodium perchlorate aids in the complete removal of proteins from nucleic acids, simplifying the isolation process and reducing the risk of degradation or contamination.

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