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Staurosporine / 10 MG

Molecular Formula: C28H26N4O3
Molecular Weight: 466.53
SKU: MND-17588
CAS Number: 62996-74-1
MDL number: MFCD00077402
Packing size: 10 MG  



Safety Information


Hazard Statements

H361d
H413

Precautionary Statements

P202
P280
P273
P308 + P313
P405
P201

Pictograms



Properties

Signal WordWarning
Flash Point (C)Not available
Flash Point (F)Not available

 Product Description

Staurosporine is a natural product isolated from bacteria and exhibits potent inhibitory activity against various protein kinases. It is widely used in research laboratories as a tool compound for studying signal transduction pathways and cellular processes.

 

Application:

Staurosporine is primarily employed in biomedical research as a pharmacological agent to study protein kinase activity, cell signaling, and apoptosis. It is also investigated for its potential therapeutic applications in cancer treatment and neurodegenerative diseases.

 

 

Articles:

- Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways

Publication Date: FEBRUARY 25 2004

Xu Dong Zhang; Susan K. Gillespie; Peter Hersey

https://doi.org/10.1158/1535-7163.187.3.2

 

- Human αA- and αB-crystallins bind to Bax and Bcl-XS to sequester their translocation during staurosporine-induced apoptosis

Publication Date: 30 January 2004

Y-W Mao, J-P Liu, H Xiang & D W-C Li

https://doi.org/10.1038/sj.cdd.4401384

 

- Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study

Publication Date: 08 June 2009

Yanyan Wang, Hongfa Yang, Hongbin Liu, Ji Huang & Xingfu Song

https://doi.org/10.1186/1471-2407-9-174